Upfront dilution of ferritin samples to reduce hook effect, improve turnaround time and reduce costs

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Upfront dilution of ferritin samples to reduce hook effect, improve turnaround time and reduce costs

Introduction Sandwich immunoassays offer advantages in the clinical laboratory but can yield erroneously low results due to hook (prozone) effect, especially with analytes whose concentrations span several orders of magnitude such as ferritin. This study investigated a new approach to reduce the likelihood of hook effect in ferritin immunoassays by performing upfront, five-fold dilutions of all...

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ژورنال

عنوان ژورنال: Biochemia Medica

سال: 2017

ISSN: 1330-0962,1846-7482

DOI: 10.11613/bm.2018.010903